Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
---|---|---|---|---|---|---|---|---|
ELMI002687 | O95644 NFATC1 NFAC1_HUMAN |
387 | 390 | KGGFCDQYLAVPQHPYQWAK | TP | --- | Homo sapiens (Human) | 943 |
Instance evidence
Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
---|---|---|---|---|---|---|---|
experimental | MI:0096 | pull down | in vivo/in vitro | support | certain | InteractionDetection | |
experimental | MI:0519 | glutathione s tranferase tag | in vitro | Rodriguez,2009 | support | certain | |
experimental | MI:0096 | pull down | in vivo/in vitro | support | certain | InteractionDetection | |
experimental | MI:0519 | glutathione s tranferase tag | in vitro | Park,2000 | support | certain | |
experimental | MI:0096 | pull down | in vivo/in vitro | support | certain | InteractionDetection | |
experimental | MI:0519 | glutathione s tranferase tag | in vitro | Martinez-Martinez,2006 | support | certain | |
experimental | MI:0405 | competition binding | in vitro | Martinez-Martinez,2006 | support | certain | InteractionDetection |
experimental | MI:0077 | nuclear magnetic resonance | in vitro | Park,2000 | support | certain | InteractionDetection FeatureDetection |
experimental | MI:0506 | over expressed level | in vivo | Park,2000 | support | certain | |
experimental | MI:0405 | competition binding | in vitro | Park,2000 | support | certain | InteractionDetection |
experimental | MI:0065 | isothermal titration calorimetry | in vitro | Park,2000 | support | certain | InteractionDetection |
experimental | MI:0074 | mutation analysis | in vivo/in vitro | Park,2000 | support | certain | FeatureDetection |
experimental | MI:0074 | mutation analysis | in vivo/in vitro | Rodriguez,2009 | support | certain | FeatureDetection |
experimental | MI:0405 | competition binding | in vitro | Rodriguez,2009 | support | certain | InteractionDetection |
Interactions
Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
---|---|---|---|---|---|
(P63098) CANB1_HUMAN | PF13499
(EF_hand_7)
EF-hand domain pair |
[mitab][xml] | |||
(Q08209) PP2BA_HUMAN | PF00149
(Metallophos)
Calcineurin-like phosphoesterase |
83 | 285 | 1.3/1.3 | [mitab][xml] |
Pathways
KEGG: The sequence O95644 is implicated in the following 23 Pathways: (color codes: This sequence=red, interacting sequence=orange)- AGE RAGE signaling pathway in diabetic complications
- B cell receptor signaling pathway
- C type lectin receptor signaling pathway
- Cellular senescence
- Hepatitis B
- Human T cell leukemia virus 1 infection
- Human cytomegalovirus infection
- Human immunodeficiency virus 1 infection
- Inflammatory bowel disease
- Kaposi sarcoma associated herpesvirus infection
- Lipid and atherosclerosis
- MAPK signaling pathway
- Natural killer cell mediated cytotoxicity
- Osteoclast differentiation
- Oxytocin signaling pathway
- PD L1 expression and PD 1 checkpoint pathway in cancer
- T cell receptor signaling pathway
- Th1 and Th2 cell differentiation
- Th17 cell differentiation
- Wnt signaling pathway
- Yersinia infection
- cAMP signaling pathway
- cGMP PKG signaling pathway
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement