The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI002287 P06400 RB1
RB_HUMAN
871 878 GSNPPKPLKKLRFDIEGSDE TP 3N5U  
pdb:3N5U
Homo sapiens (Human) 928

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0434 phosphatase assay in vitro Hirschi,2010 support certain InteractionDetection
experimental MI:0114 x-ray crystallography in vitro Hirschi,2010 support certain InteractionDetection FeatureDetection
experimental MI:0074 mutation analysis in vivo/in vitro Hirschi,2010 support certain FeatureDetection
experimental MI:0065 isothermal titration calorimetry in vitro Hirschi,2010 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P62136) PP1A_HUMAN PF00149 (Metallophos)
Calcineurin-like phosphoesterase
57 252 3.9/3.9 [mitab][xml]

o  Pathways

KEGG: The sequence P06400 is implicated in the following 14 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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