Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
---|---|---|---|---|---|---|---|---|
ELMI002287 | P06400 RB1 RB_HUMAN |
871 | 878 | GSNPPKPLKKLRFDIEGSDE | TP |
3N5U |
Homo sapiens (Human) | 928 |
Instance evidence
Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
---|---|---|---|---|---|---|---|
experimental | MI:0434 | phosphatase assay | in vitro | Hirschi,2010 | support | certain | InteractionDetection |
experimental | MI:0114 | x-ray crystallography | in vitro | Hirschi,2010 | support | certain | InteractionDetection FeatureDetection |
experimental | MI:0074 | mutation analysis | in vivo/in vitro | Hirschi,2010 | support | certain | FeatureDetection |
experimental | MI:0065 | isothermal titration calorimetry | in vitro | Hirschi,2010 | support | certain | InteractionDetection |
Interactions
Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
---|---|---|---|---|---|
(P62136) PP1A_HUMAN | PF00149
(Metallophos)
Calcineurin-like phosphoesterase |
57 | 252 | 3.9/3.9 | [mitab][xml] |
Pathways
KEGG: The sequence P06400 is implicated in the following 25 Pathways: (color codes: This sequence=red, interacting sequence=orange)- Bladder cancer
- Breast cancer
- Cell cycle
- Cellular senescence
- Chemical carcinogenesis receptor activation
- Chronic myeloid leukemia
- Cushing syndrome
- Endocrine resistance
- Epstein Barr virus infection
- Gastric cancer
- Glioma
- Hepatitis B
- Hepatitis C
- Hepatocellular carcinoma
- Human T cell leukemia virus 1 infection
- Human cytomegalovirus infection
- Human papillomavirus infection
- Kaposi sarcoma associated herpesvirus infection
- Melanoma
- Non small cell lung cancer
- Pancreatic cancer
- Pathways in cancer
- Prostate cancer
- Small cell lung cancer
- Viral carcinogenesis
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement