Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
---|---|---|---|---|---|---|---|---|
ELMI002941 | P49137 MAPKAPK2 MAPK2_HUMAN |
370 | 386 | QIKIKKIEDASNPLLLKRRK | TP |
2OKR 4TYH |
Homo sapiens (Human) | 400 |
Instance evidence
Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
---|---|---|---|---|---|---|---|
experimental | MI:0096 | pull down | in vivo/in vitro | support | certain | InteractionDetection | |
experimental | MI:0519 | glutathione s tranferase tag | in vitro | Garai,2012 | support | certain | |
experimental | MI:0096 | pull down | in vivo/in vitro | support | certain | InteractionDetection | |
experimental | MI:0519 | glutathione s tranferase tag | in vitro | Cumming,2015 | support | certain | |
experimental | MI:0405 | competition binding | in vitro | Cumming,2015 | support | certain | InteractionDetection |
experimental | MI:0114 | x-ray crystallography | in vitro | Cumming,2015 | support | certain | InteractionDetection FeatureDetection |
experimental | MI:0051 | fluorescence technology | Garai,2012 | support | certain | InteractionDetection | |
experimental | MI:0405 | competition binding | in vitro | Garai,2012 | support | certain | InteractionDetection |
experimental | MI:0114 | x-ray crystallography | in vitro | Garai,2012 | support | certain | InteractionDetection FeatureDetection |
Interactions
Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
---|---|---|---|---|---|
(P28482) MK01_HUMAN | PF00069
(Pkinase)
Protein kinase domain |
25 | 313 | 19.5/19.5 | [mitab][xml] |
(Q16539) MK14_HUMAN | PF00069
(Pkinase)
Protein kinase domain |
24 | 308 | 0.05/0.05 | [mitab][xml] |
Pathways
KEGG: The sequence P49137 is implicated in the following 7 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement