The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003096 Q12968 NFATC3
NFAC3_HUMAN
146 154 LERPSRDHLYLPLEPSYRES TP 2XS0  
Homo sapiens (Human) 1075

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0053 fluorescence polarization spectroscopy in vitro Garai,2012 support certain InteractionDetection
experimental MI:0424 protein kinase assay in vivo Garai,2012 support certain InteractionDetection
experimental MI:0114 x-ray crystallography in vitro Garai,2012 support certain InteractionDetection FeatureDetection
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Garai,2012 support certain FeatureDetection
experimental MI:0424 protein kinase assay in vitro Chow,1997 support certain InteractionDetection
experimental MI:0424 protein kinase assay in vivo Chow,1997 support certain InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Chow,1997 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P45983) MK08_HUMAN PF00069 (Pkinase)
Protein kinase domain
26 321 [mitab][xml]
(P45984) MK09_HUMAN PF00069 (Pkinase)
Protein kinase domain
26 321 [mitab][xml]

o  Pathways

KEGG: The sequence Q12968 is implicated in the following 9 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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