| Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
|---|---|---|---|---|---|---|---|---|
| ELMI003096 | Q12968 NFATC3 NFAC3_HUMAN |
146 | 154 | LERPSRDHLYLPLEPSYRES | TP |
2XS0 |
Homo sapiens (Human) | 1075 |
Instance evidence
| Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
|---|---|---|---|---|---|---|---|
| experimental | MI:0053 | fluorescence polarization spectroscopy | in vitro | Garai,2012 | support | certain | InteractionDetection |
| experimental | MI:0424 | protein kinase assay | in vivo | Garai,2012 | support | certain | InteractionDetection |
| experimental | MI:0114 | x-ray crystallography | in vitro | Garai,2012 | support | certain | InteractionDetection FeatureDetection |
| experimental | MI:0005 | alanine scanning | in vivo/in vitro/in silico | Garai,2012 | support | certain | FeatureDetection |
| experimental | MI:0424 | protein kinase assay | in vitro | Chow,1997 | support | certain | InteractionDetection |
| experimental | MI:0424 | protein kinase assay | in vivo | Chow,1997 | support | certain | InteractionDetection |
| experimental | MI:0019 | coimmunoprecipitation | in vivo/in vitro | Chow,1997 | support | certain | InteractionDetection |
Interactions
| Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
|---|---|---|---|---|---|
| (P45983) MK08_HUMAN | PF00069
(Pkinase)
Protein kinase domain |
26 | 321 | [mitab][xml] | |
| (P45984) MK09_HUMAN | PF00069
(Pkinase)
Protein kinase domain |
26 | 321 | [mitab][xml] |
Pathways
- Axon guidance
- B cell receptor signaling pathway
- C type lectin receptor signaling pathway
- Cellular senescence
- Hepatitis B
- Human T cell leukemia virus 1 infection
- Human cytomegalovirus infection
- Human immunodeficiency virus 1 infection
- Kaposi sarcoma associated herpesvirus infection
- Lipid and atherosclerosis
- MAPK signaling pathway
- Oxytocin signaling pathway
- PD L1 expression and PD 1 checkpoint pathway in cancer
- T cell receptor signaling pathway
- Th1 and Th2 cell differentiation
- Th17 cell differentiation
- Wnt signaling pathway
- Yersinia infection
- cGMP PKG signaling pathway
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement