The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003090 P45985 MAP2K4
MP2K4_HUMAN
41 49 SMQGKRKALKLNFANPPFKS TP --- Homo sapiens (Human) 399

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0405 competition binding in vitro Garai,2012 support certain InteractionDetection
experimental MI:0424 protein kinase assay in vivo Bardwell,2015 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Bardwell,2015 support certain FeatureDetection
experimental MI:0405 competition binding in vitro Ho,2003 support certain InteractionDetection
experimental MI:0027 cosedimentation in vitro Ho,2003 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Ho,2003 support certain FeatureDetection
experimental MI:0424 protein kinase assay in vivo Ho,2003 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P45983) MK08_HUMAN PF00069 (Pkinase)
Protein kinase domain
26 321 [mitab][xml]
(P45983-2) MK08_HUMAN PF00069 (Pkinase)
Protein kinase domain
26 321 [mitab][xml]
(P45984) MK09_HUMAN PF00069 (Pkinase)
Protein kinase domain
26 321 [mitab][xml]
(P53779) MK10_HUMAN PF00069 (Pkinase)
Protein kinase domain
64 359 [mitab][xml]

o  Pathways

KEGG: The sequence P45985 is implicated in the following 12 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
feedback@elm.eu.org