| Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
|---|---|---|---|---|---|---|---|---|
| ELMI003090 | P45985 MAP2K4 MP2K4_HUMAN |
41 | 49 | SMQGKRKALKLNFANPPFKS | TP | --- | Homo sapiens (Human) | 399 |
Instance evidence
| Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
|---|---|---|---|---|---|---|---|
| experimental | MI:0405 | competition binding | in vitro | Garai,2012 | support | certain | InteractionDetection |
| experimental | MI:0424 | protein kinase assay | in vivo | Bardwell,2015 | support | certain | InteractionDetection |
| experimental | MI:0074 | mutation analysis | in vivo/in vitro | Bardwell,2015 | support | certain | FeatureDetection |
| experimental | MI:0405 | competition binding | in vitro | Ho,2003 | support | certain | InteractionDetection |
| experimental | MI:0027 | cosedimentation | in vitro | Ho,2003 | support | certain | InteractionDetection |
| experimental | MI:0074 | mutation analysis | in vivo/in vitro | Ho,2003 | support | certain | FeatureDetection |
| experimental | MI:0424 | protein kinase assay | in vivo | Ho,2003 | support | certain | InteractionDetection |
Interactions
| Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
|---|---|---|---|---|---|
| (P45983) MK08_HUMAN | PF00069
(Pkinase)
Protein kinase domain |
26 | 321 | [mitab][xml] | |
| (P45983-2) MK08_HUMAN | PF00069
(Pkinase)
Protein kinase domain |
26 | 321 | [mitab][xml] | |
| (P45984) MK09_HUMAN | PF00069
(Pkinase)
Protein kinase domain |
26 | 321 | [mitab][xml] | |
| (P53779) MK10_HUMAN | PF00069
(Pkinase)
Protein kinase domain |
64 | 359 | [mitab][xml] |
Pathways
- Chagas disease
- Chemical carcinogenesis reactive oxygen species
- Epithelial cell signaling in Helicobacter pylori infection
- Epstein Barr virus infection
- ErbB signaling pathway
- Fc epsilon RI signaling pathway
- Fluid shear stress and atherosclerosis
- GnRH signaling pathway
- Growth hormone synthesis, secretion and action
- Hepatitis B
- Human T cell leukemia virus 1 infection
- Kaposi sarcoma associated herpesvirus infection
- Lipid and atherosclerosis
- MAPK signaling pathway
- Relaxin signaling pathway
- Salmonella infection
- TNF signaling pathway
- Toll like receptor signaling pathway
- Yersinia infection
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement