The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003048 P01100 FOS
FOS_HUMAN
343 346 TAYTSSFVFTYPEADSFPSC TP --- Homo sapiens (Human) 380

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0107 surface plasmon resonance in vitro Burkhard,2011 support certain InteractionDetection FeatureDetection
experimental MI:0074 mutation analysis in vivo/in vitro Burkhard,2011 support certain FeatureDetection
experimental MI:0405 competition binding in vitro Murphy,2002 support certain InteractionDetection
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Murphy,2002 support certain FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P28482) MK01_HUMAN PF00069 (Pkinase)
Protein kinase domain
25 313 [mitab][xml]
(P27361) MK03_HUMAN PF00069 (Pkinase)
Protein kinase domain
42 330 [mitab][xml]

o  Pathways

KEGG: The sequence P01100 is implicated in the following 25 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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