| Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
|---|---|---|---|---|---|---|---|---|
| ELMI003048 | P01100 FOS FOS_HUMAN |
343 | 346 | TAYTSSFVFTYPEADSFPSC | TP | --- | Homo sapiens (Human) | 380 |
Instance evidence
| Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
|---|---|---|---|---|---|---|---|
| experimental | MI:0107 | surface plasmon resonance | in vitro | Burkhard,2011 | support | certain | InteractionDetection FeatureDetection |
| experimental | MI:0074 | mutation analysis | in vivo/in vitro | Burkhard,2011 | support | certain | FeatureDetection |
| experimental | MI:0405 | competition binding | in vitro | Murphy,2002 | support | certain | InteractionDetection |
| experimental | MI:0005 | alanine scanning | in vivo/in vitro/in silico | Murphy,2002 | support | certain | FeatureDetection |
Interactions
| Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
|---|---|---|---|---|---|
| (P28482) MK01_HUMAN | PF00069
(Pkinase)
Protein kinase domain |
25 | 313 | [mitab][xml] | |
| (P27361) MK03_HUMAN | PF00069
(Pkinase)
Protein kinase domain |
42 | 330 | [mitab][xml] |
Pathways
- Amphetamine addiction
- Apoptosis
- B cell receptor signaling pathway
- Breast cancer
- Chagas disease
- Chemical carcinogenesis reactive oxygen species
- Chemical carcinogenesis receptor activation
- Choline metabolism in cancer
- Cholinergic synapse
- Circadian entrainment
- Colorectal cancer
- Coronavirus disease COVID 19
- Dopaminergic synapse
- Endocrine resistance
- Estrogen signaling pathway
- Fluid shear stress and atherosclerosis
- Growth hormone synthesis, secretion and action
- Hepatitis B
- Human T cell leukemia virus 1 infection
- Human immunodeficiency virus 1 infection
- IL 17 signaling pathway
- Kaposi sarcoma associated herpesvirus infection
- Leishmaniasis
- Lipid and atherosclerosis
- MAPK signaling pathway
- Measles
- Non alcoholic fatty liver disease
- Osteoclast differentiation
- Oxytocin signaling pathway
- PD L1 expression and PD 1 checkpoint pathway in cancer
- Parathyroid hormone synthesis, secretion and action
- Pathogenic Escherichia coli infection
- Pathways in cancer
- Pertussis
- Prolactin signaling pathway
- Relaxin signaling pathway
- Rheumatoid arthritis
- Salmonella infection
- T cell receptor signaling pathway
- TNF signaling pathway
- Th1 and Th2 cell differentiation
- Th17 cell differentiation
- Toll like receptor signaling pathway
- Yersinia infection
- cAMP signaling pathway
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement