Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
---|---|---|---|---|---|---|---|---|
ELMI002876 | O15169 AXIN1 AXIN1_HUMAN |
383 | 399 | RVEPQKFAEELIHRLEAVQR | TP |
1O9U |
Homo sapiens (Human) | 862 |
Instance evidence
Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
---|---|---|---|---|---|---|---|
experimental | MI:0114 | x-ray crystallography | in vitro | Dajani,2003 | support | certain | InteractionDetection FeatureDetection |
experimental | MI:0010 | beta galactosidase complementation | Howng,2010 | support | certain | InteractionDetection | |
experimental | MI:0096 | pull down | in vivo/in vitro | Howng,2010 | support | certain | InteractionDetection |
experimental | MI:0074 | mutation analysis | in vivo/in vitro | Howng,2010 | support | certain | FeatureDetection |
Interactions
Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
---|---|---|---|---|---|
(P49841) GSK3B_HUMAN | PF00069
(Pkinase)
Protein kinase domain |
56 | 340 | [mitab][xml] |
Pathways
KEGG: The sequence O15169 is implicated in the following 14 Pathways: (color codes: This sequence=red, interacting sequence=orange)- Alzheimer disease
- Basal cell carcinoma
- Breast cancer
- Colorectal cancer
- Cushing syndrome
- Endometrial cancer
- Gastric cancer
- Hepatocellular carcinoma
- Hippo signaling pathway
- Human papillomavirus infection
- Pathways in cancer
- Pathways of neurodegeneration multiple diseases
- Signaling pathways regulating pluripotency of stem cells
- Wnt signaling pathway
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement