The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI002876 O15169 AXIN1
AXIN1_HUMAN
383 399 RVEPQKFAEELIHRLEAVQR TP 1O9U  
Homo sapiens (Human) 862

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0114 x-ray crystallography in vitro Dajani,2003 support certain InteractionDetection FeatureDetection
experimental MI:0010 beta galactosidase complementation Howng,2010 support certain InteractionDetection
experimental MI:0096 pull down in vivo/in vitro Howng,2010 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Howng,2010 support certain FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P49841) GSK3B_HUMAN PF00069 (Pkinase)
Protein kinase domain
56 340 [mitab][xml]

o  Pathways

KEGG: The sequence O15169 is implicated in the following 14 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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