The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004790 Q13309 SKP2
SKP2_HUMAN
78 89 GSDKDFVIVRRPKLNRENFP TP 7LUO  
Homo sapiens (Human) 424

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0586 inhibitor Kelso,2021 support certain
experimental MI:0065 isothermal titration calorimetry in vitro Kelso,2021 support certain InteractionDetection
experimental MI:0405 competition binding in vitro Kelso,2021 support certain InteractionDetection
experimental MI:0033 deletion analysis Kelso,2021 support certain FeatureDetection
experimental MI:0074 mutation analysis in vivo/in vitro Kelso,2021 support certain FeatureDetection
experimental MI:0573 mutation disrupting interaction in vivo/in vitro Kelso,2021 support certain
experimental MI:0053 fluorescence polarization spectroscopy in vitro Kelso,2021 support certain InteractionDetection
experimental MI:0114 x-ray crystallography in vitro Kelso,2021 support certain InteractionDetection FeatureDetection
experimental MI:0091 chromatography technology in vitro Kelso,2021 support certain InteractionDetection
experimental MI:0004 affinity chromatography technology in vivo/in vitro Kelso,2021 support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Kelso,2021 support certain
experimental MI:0096 pull down in vivo/in vitro Kelso,2021 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P20248) CCNA2_HUMAN IPR006671 (Cyclin, N-terminal)
Cyclins contain two domains of similar all-alpha fold, of which this entry is associated with the N-terminal domain
181 306 3.2/3.2 [mitab][xml]

o  Pathways

KEGG: The sequence Q13309 is implicated in the following 8 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The Eukaryotic Linear Motif resource: 2022 release. (PMID:34718738)

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