| Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
|---|---|---|---|---|---|---|---|---|
| ELMI002058 | O15169 AXIN1 AXIN1_HUMAN |
21 | 28 | SFTEDAPRPPVPGEEGELVS | TP | --- | Homo sapiens (Human) | 862 |
Instance evidence
| Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
|---|---|---|---|---|---|---|---|
| experimental | MI:0096 | pull down | in vivo/in vitro | support | certain | InteractionDetection | |
| experimental | MI:0519 | glutathione s tranferase tag | in vitro | Huang,2009 | support | certain | |
| experimental | MI:0019 | coimmunoprecipitation | in vivo/in vitro | Huang,2009 | support | certain | InteractionDetection |
| experimental | MI:0053 | fluorescence polarization spectroscopy | in vitro | Guettler,2011 | support | likely | InteractionDetection |
| experimental | MI:0005 | alanine scanning | in vivo/in vitro/in silico | Guettler,2011 | support | likely | FeatureDetection |
Interactions
| Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
|---|---|---|---|---|---|
| (O95271) TNKS1_HUMAN | PF00023
(Ank)
Ankyrin repeat |
[mitab][xml] | |||
| (Q9H2K2) TNKS2_HUMAN | PF00023
(Ank)
Ankyrin repeat |
525 | 557 | [mitab][xml] |
Pathways
- Alzheimer disease
- Basal cell carcinoma
- Breast cancer
- Colorectal cancer
- Cushing syndrome
- Endometrial cancer
- Gastric cancer
- Hepatocellular carcinoma
- Hippo signaling pathway
- Human papillomavirus infection
- Pathways in cancer
- Pathways of neurodegeneration multiple diseases
- Signaling pathways regulating pluripotency of stem cells
- Wnt signaling pathway
Please cite:
The Eukaryotic Linear Motif resource: 2022 release.
(PMID:34718738)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement