The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI001639 Q16513 PKN2
PKN2_HUMAN
974 979 ILSEEEQEMFRDFDYIADWC TP --- Homo sapiens (Human) 984

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Balendran,2000 support certain
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Biondi,2000 support certain
experimental MI:0004 affinity chromatography technology in vivo/in vitro Collins,2005 support certain InteractionDetection
experimental MI:0113 western blot in vitro Collins,2005 support certain ParticipantIdentification FeatureDetection
experimental MI:0074 mutation analysis in vivo/in vitro Collins,2005 support certain FeatureDetection
experimental MI:0018 two hybrid in vivo Biondi,2000 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Biondi,2000 support certain FeatureDetection
experimental MI:0107 surface plasmon resonance in vitro Biondi,2000 support certain InteractionDetection FeatureDetection
experimental MI:0018 two hybrid in vivo Balendran,2000 support certain InteractionDetection
experimental MI:0405 competition binding in vitro Balendran,2000 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Balendran,2000 support certain FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(O15530) PDPK1_HUMAN PF00069 (Pkinase)
Protein kinase domain
82 341 [mitab][xml]

o  Pathways

KEGG: The sequence Q16513 is implicated in the following 2 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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