ELM - instance DOC_AGCK_PIF_2 in sequence Q16513 at position 974

Instance

Accession	Acc. Gene-, Name	Start	End	Subsequence	Logic	PDB	Organism	Length
ELMI001639	Q16513 PKN2 PKN2_HUMAN	974	979	ILSEEEQEMFRDFDYIADWC	TP	---	Homo sapiens (Human)	984

Instance evidence

Evidence class	PSI-MI	Method	BioSource	PubMed	Logic	Reliability	Notes
experimental	MI:0096	pull down	in vivo/in vitro		support	certain	InteractionDetection
experimental	MI:0519	glutathione s tranferase tag	in vitro	Balendran,2000	support	certain
experimental	MI:0096	pull down	in vivo/in vitro		support	certain	InteractionDetection
experimental	MI:0519	glutathione s tranferase tag	in vitro	Biondi,2000	support	certain
experimental	MI:0004	affinity chromatography technology	in vivo/in vitro	Collins,2005	support	certain	InteractionDetection
experimental	MI:0113	western blot	in vitro	Collins,2005	support	certain	ParticipantIdentification FeatureDetection
experimental	MI:0074	mutation analysis	in vivo/in vitro	Collins,2005	support	certain	FeatureDetection
experimental	MI:0018	two hybrid	in vivo	Biondi,2000	support	certain	InteractionDetection
experimental	MI:0074	mutation analysis	in vivo/in vitro	Biondi,2000	support	certain	FeatureDetection
experimental	MI:0107	surface plasmon resonance	in vitro	Biondi,2000	support	certain	InteractionDetection FeatureDetection
experimental	MI:0018	two hybrid	in vivo	Balendran,2000	support	certain	InteractionDetection
experimental	MI:0405	competition binding	in vitro	Balendran,2000	support	certain	InteractionDetection
experimental	MI:0074	mutation analysis	in vivo/in vitro	Balendran,2000	support	certain	FeatureDetection

Interactions

Uniprot Id	Domain family	Domain Start	Domain End	Affinity Min/Max (µMol)	Notes
(O15530) PDPK1_HUMAN	PF00069 (Pkinase) Protein kinase domain	82	341		[mitab][xml]

Pathways

KEGG: The sequence Q16513 is implicated in the following 3 Pathways: (color codes: This sequence=red, interacting sequence=orange)

Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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