The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI001220 Q16665 HIF1A
HIF1A_HUMAN
562 574 LEMLAPYIPMDDDFQLRSFD TP 1LM8  
pdb:1LM8 1LQB  
pdb:1LQB
Homo sapiens (Human) 826

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0114 x-ray crystallography in vitro Hon,2002 support certain InteractionDetection FeatureDetection
experimental MI:0065 isothermal titration calorimetry in vitro Min,2002 support certain InteractionDetection
experimental MI:0107 surface plasmon resonance in vitro Hon,2002 support certain InteractionDetection FeatureDetection

o  Switches



This ELM instance is part of the following 1 switching mechanism annotated at the switches.ELM resource:

o  Pathways

KEGG: The sequence Q16665 is implicated in the following 8 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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