ELM - instance CLV_C14_Caspase3-7 in sequence Q13043 at position 323

Instance

Accession	Acc. Gene-, Name	Start	End	Subsequence	Logic	PDB	Organism	Length
ELMI001902	Q13043 STK4 STK4_HUMAN	323	327	DEENSEEDEMDSGTMVRAVG	TP	---	Homo sapiens (Human)	487

Instance evidence

Evidence class	PSI-MI	Method	BioSource	PubMed	Logic	Reliability	Notes
experimental	MI:0074	mutation analysis	in vivo/in vitro	Graves,2001	support	likely	FeatureDetection
experimental	MI:0194	cleavage reaction	in vivo/in vitro	Graves,2001	support	likely	InteractionDetection
experimental	MI:0017	classical fluorescence spectroscopy	in vitro	Lee,2001	support	likely	InteractionDetection
experimental	MI:0113	western blot	in vitro	Lee,2001	support	likely	ParticipantIdentification FeatureDetection
experimental	MI:0074	mutation analysis	in vivo/in vitro	Lee,2001	support	likely	FeatureDetection
experimental	MI:0194	cleavage reaction	in vivo/in vitro	Lee,2001	support	likely	InteractionDetection

Interactions

Uniprot Id	Domain family	Domain Start	Domain End	Affinity Min/Max (µMol)	Notes
(P42574) CASP3_HUMAN	PF00656 (Peptidase_C14) Caspase domain	45	275		[mitab][xml]

Pathways

KEGG: The sequence Q13043 is implicated in the following 5 Pathways: (color codes: This sequence=red, interacting sequence=orange)

Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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