The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI001902 Q13043 STK4
STK4_HUMAN
323 327 DEENSEEDEMDSGTMVRAVG TP --- Homo sapiens (Human) 487

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0074 mutation analysis in vivo/in vitro Graves,2001 support likely FeatureDetection
experimental MI:0194 cleavage reaction in vivo/in vitro Graves,2001 support likely InteractionDetection
experimental MI:0017 classical fluorescence spectroscopy in vitro Lee,2001 support likely InteractionDetection
experimental MI:0113 western blot in vitro Lee,2001 support likely ParticipantIdentification FeatureDetection
experimental MI:0074 mutation analysis in vivo/in vitro Lee,2001 support likely FeatureDetection
experimental MI:0194 cleavage reaction in vivo/in vitro Lee,2001 support likely InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P42574) CASP3_HUMAN PF00656 (Peptidase_C14)
Caspase domain
45 275 [mitab][xml]

o  Pathways

KEGG: The sequence Q13043 is implicated in the following 5 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The Eukaryotic Linear Motif resource: 2022 release. (PMID:34718738)

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