Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
---|---|---|---|---|---|---|---|---|
ELMI004923 | Q86WV6 TMEM173 STING_HUMAN |
369 | 377 | EPELLISGMEKPLPLRTDFS | TP |
6O8C |
Homo sapiens (Human) | 379 |
Instance evidence
Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
---|---|---|---|---|---|---|---|
experimental | MI:0119 | mutation decreasing interaction | in vivo/in vitro | Zhang,2019 | support | certain | InteractionDetection |
experimental | MI:0119 | mutation decreasing interaction | in vivo/in vitro | Zhao,2019 | support | certain | InteractionDetection |
experimental | MI:0019 | coimmunoprecipitation | in vivo/in vitro | Zhao,2019 | support | certain | InteractionDetection |
experimental | MI:0114 | x-ray crystallography | in vitro | Zhao,2019 | support | certain | InteractionDetection FeatureDetection |
Interactions
Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
---|---|---|---|---|---|
(Q9UHD2) TBK1_HUMAN | IPR000719
(Protein kinase domain)
Protein phosphorylation, which plays a key role in most cellular activities, is a reversible process mediated by protein kinases and phosphoprotein phosphatases |
9 | 310 | [mitab][xml] | |
(Q9UHD2) TBK1_HUMAN | IPR041309
(TANK-binding kinase 1, coiled-coil domain 1)
This is a coiled-coil domain found in TANK-binding kinase 1 (TBK1), it comprises one of two coiled-coil domains found in the scaffold dimerization region |
400 | 655 | [mitab][xml] |
Pathways
KEGG: The sequence Q86WV6 is implicated in the following 8 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement