The Eukaryotic Linear Motif resource for
Functional Sites in Proteins
DOC_TBK1_STING_1

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004922 E1C7U0 STING1
STING_CHICK 		369 377 ELSLQVSSSDLPQPLRSDCP TP 6NT9  
Gallus gallus (Chicken) 379

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0040 electron microscopy in vivo/in vitro Zhang,2019 support likely InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Cheng,2017 support likely InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(E1C581) E1C581_CHICK IPR000719 (Protein kinase domain)
Protein phosphorylation, which plays a key role in most cellular activities, is a reversible process mediated by protein kinases and phosphoprotein phosphatases 		9 310 [mitab][xml]
(E1C581) E1C581_CHICK IPR041309 (TANK-binding kinase 1, coiled-coil domain 1)
This is a coiled-coil domain found in TANK-binding kinase 1 (TBK1), it comprises one of two coiled-coil domains found in the scaffold dimerization region 		400 655 [mitab][xml]
(Q9UHD2) TBK1_HUMAN IPR000719 (Protein kinase domain)
Protein phosphorylation, which plays a key role in most cellular activities, is a reversible process mediated by protein kinases and phosphoprotein phosphatases 		9 310 [mitab][xml]
(Q9UHD2) TBK1_HUMAN IPR041309 (TANK-binding kinase 1, coiled-coil domain 1)
This is a coiled-coil domain found in TANK-binding kinase 1 (TBK1), it comprises one of two coiled-coil domains found in the scaffold dimerization region 		400 655 [mitab][xml]
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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