The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004896 Q63767 Bcar1
BCAR1_RAT
760 766 SEGGWMEDYDYVHLQGKEEF TP 1X27  
Rattus norvegicus (Norway rat) 968

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro Nasertorabi,2006 support certain InteractionDetection
experimental MI:0107 surface plasmon resonance in vitro Nasertorabi,2006 support certain InteractionDetection FeatureDetection
experimental MI:0114 x-ray crystallography in vitro Nasertorabi,2006 support certain InteractionDetection FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P06239) LCK_HUMAN IPR000980 (SH2 domain)
The Src homology 2 (SH2) domain is a protein domain of about 100 amino-acid residues first identified as a conserved sequence region between the oncoproteins Src and Fps
125 224 0.025/0.046 [mitab][xml]

o  Pathways

KEGG: The sequence Q63767 is implicated in the following 9 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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