The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004891 P00533 EGFR
EGFR_HUMAN
1090 1096 DTFLPVPEYINQSVPKRPAG TP --- Homo sapiens (Human) 1210

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0411 elisa in vitro Gay,1997 support certain InteractionDetection ParticipantIdentification

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P06240) LCK_MOUSE IPR000980 (SH2 domain)
The Src homology 2 (SH2) domain is a protein domain of about 100 amino-acid residues first identified as a conserved sequence region between the oncoproteins Src and Fps
125 224 [mitab][xml]
(P05480) SRC_MOUSE IPR000980 (SH2 domain)
The Src homology 2 (SH2) domain is a protein domain of about 100 amino-acid residues first identified as a conserved sequence region between the oncoproteins Src and Fps
148 247 [mitab][xml]

o  Pathways

KEGG: The sequence P00533 is implicated in the following 48 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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