The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004793 P22681 CBL
CBL_HUMAN
819 826 VTEGSQVPERPPKPFPRRIN TP --- Homo sapiens (Human) 906

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0017 classical fluorescence spectroscopy in vitro Lewitzky,2001 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P62993) GRB2_HUMAN IPR001452 (SH3 domain)
SH3 (src Homology-3) domains are small protein modules containing approximately 50 amino acid residues
156 215 15.49/24.05 [mitab][xml]

o  Pathways

KEGG: The sequence P22681 is implicated in the following 8 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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