The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004744 Q52LA3 LIN52
LIN52_HUMAN
15 28 TDLEASLLSFEKLDRASPDL TP 4YOS  
Homo sapiens (Human) 116

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0113 western blot in vitro James,2021 support certain ParticipantIdentification FeatureDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro James,2021 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro James,2021 support certain FeatureDetection
experimental MI:0113 western blot in vitro Guiley,2015 support certain ParticipantIdentification FeatureDetection
experimental MI:0405 competition binding in vitro Guiley,2015 support certain InteractionDetection
experimental MI:0053 fluorescence polarization spectroscopy in vitro Guiley,2015 support certain InteractionDetection
experimental MI:1019 protein phosphatase assay Guiley,2015 support certain InteractionDetection
experimental MI:0573 mutation disrupting interaction in vivo/in vitro Guiley,2015 support certain
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Guiley,2015 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Guiley,2015 support certain FeatureDetection
experimental MI:0114 x-ray crystallography in vitro Guiley,2015 support certain InteractionDetection FeatureDetection
experimental MI:0065 isothermal titration calorimetry in vitro Guiley,2015 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P28749) RBL1_HUMAN IPR002719 (Retinoblastoma-associated protein, B-box)
This entry includes retinoblastoma-associated protein (RB, also known as pRb, RB, p1051), retinoblastoma-like protein 1 (RBL1, also known as p107) and retinoblastoma-like protein 2 (RBL2, also kno...
787 943 1.4/1.4 [mitab][xml]
(Q08999) RBL2_HUMAN IPR002719 (Retinoblastoma-associated protein, B-box)
This entry includes retinoblastoma-associated protein (RB, also known as pRb, RB, p1051), retinoblastoma-like protein 1 (RBL1, also known as p107) and retinoblastoma-like protein 2 (RBL2, also kno...
835 1018 1.0/1.0 [mitab][xml]
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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