The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004702 Q13627 DYRK1A
DYR1A_HUMAN
583 586 TQVTVETHPVQETTFHVAPQ TP --- Homo sapiens (Human) 763

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0074 mutation analysis in vivo/in vitro Zhang,2021 support certain FeatureDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Zhang,2021 support certain InteractionDetection
experimental MI:0096 pull down in vivo/in vitro Zhang,2021 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q12933) TRAF2_HUMAN IPR037305 (TNF receptor-associated factor 2, MATH domain)
TNF receptor-associated factor 2 (TRAF2) regulates activation of NF-kappa-B and JNK and plays a central role in the regulation of cell survival and apoptosis
334 497 [mitab][xml]
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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