The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004681 Q5TA31 RNF187
RN187_HUMAN
232 235 QAVSELEKKHRNLGLSMLLQ TP 7OW2  
7Y3C  
Homo sapiens (Human) 235

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0997 ubiquitinase assay in vitro Ru,2022 support certain InteractionDetection
experimental MI:0113 western blot in vitro Ru,2022 support certain ParticipantIdentification FeatureDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Ru,2022 support certain InteractionDetection
experimental MI:0096 pull down in vivo/in vitro Ru,2022 support certain InteractionDetection
experimental MI:0240 fusion protein in vivo/in vitro Ru,2022 support certain InteractionDetection ParticipantIdentification
experimental MI:0065 isothermal titration calorimetry in vitro Ru,2022 support certain InteractionDetection
experimental MI:0114 x-ray crystallography in vitro Ru,2022 support certain InteractionDetection FeatureDetection
experimental MI:1311 differential scanning calorimetry Luptak,2022 support certain InteractionDetection
experimental MI:0065 isothermal titration calorimetry in vitro Luptak,2022 support certain InteractionDetection
experimental MI:0411 elisa in vitro Luptak,2022 support certain InteractionDetection ParticipantIdentification
experimental MI:0997 ubiquitinase assay in vitro Luptak,2022 support certain InteractionDetection
experimental MI:0113 western blot in vitro Luptak,2022 support certain ParticipantIdentification FeatureDetection
experimental MI:0403 colocalization in vitro Luptak,2022 support certain
experimental MI:0240 fusion protein in vivo/in vitro Luptak,2022 support certain InteractionDetection ParticipantIdentification
experimental MI:0074 mutation analysis in vivo/in vitro Luptak,2022 support certain FeatureDetection
experimental MI:0114 x-ray crystallography in vitro Luptak,2022 support certain InteractionDetection FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q9C029) TRIM7_HUMAN IPR003877 (SPRY domain)
The SPRY domain is named from SPla and the RYanodine Receptor and it is found in many eukaryotic proteins with a wide range of functions
394 507 [mitab][xml]
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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