The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004666 O15381 NVL
NVL_HUMAN
173 179 KDSEGGWFIDKTPSVKKDSF TP 6RO1  
Homo sapiens (Human) 856

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Lingaraju,2019 support certain InteractionDetection
experimental MI:0114 x-ray crystallography in vitro Lingaraju,2019 support certain InteractionDetection FeatureDetection
experimental MI:0077 nuclear magnetic resonance in vitro Lingaraju,2019 support certain InteractionDetection FeatureDetection
experimental MI:0065 isothermal titration calorimetry in vitro Lingaraju,2019 support certain InteractionDetection
experimental MI:0808 comigration in sds page in vitro Lingaraju,2019 support certain InteractionDetection
experimental MI:1247 microscale thermophoresis in vitro Lingaraju,2019 support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Lingaraju,2019 support certain
experimental MI:0074 mutation analysis in vivo/in vitro Lingaraju,2019 support certain FeatureDetection
experimental MI:0096 pull down in vivo/in vitro Lingaraju,2019 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P42285) MTREX_HUMAN IPR025696 (rRNA-processing arch domain)
The essential RNA helicase Mtr4 is an exosome-activating cofactor
582 841 0.932/1.182 [mitab][xml]
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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