The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004663 Q12080 NOP53
NOP53_YEAST
61 67 LQNDALFHVDVEGDEILKNK TP 5OOQ  
Saccharomyces cerevisiae S288c 455

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro Falk,2017 support certain InteractionDetection
experimental MI:0077 nuclear magnetic resonance in vitro Falk,2017 support certain InteractionDetection FeatureDetection
experimental MI:0114 x-ray crystallography in vitro Falk,2017 support certain InteractionDetection FeatureDetection
experimental MI:0065 isothermal titration calorimetry in vitro Falk,2017 support certain InteractionDetection
experimental MI:0069 mass spectrometry studies of complexes Thoms,2015 support certain InteractionDetection
experimental MI:0676 tandem affinity purification Thoms,2015 support certain InteractionDetection
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Thoms,2015 support certain FeatureDetection
experimental MI:0074 mutation analysis in vivo/in vitro Thoms,2015 support certain FeatureDetection
experimental MI:0033 deletion analysis Thoms,2015 support certain FeatureDetection
experimental MI:0519 glutathione s tranferase tag in vitro Thoms,2015 support certain
experimental MI:0018 two hybrid in vivo Thoms,2015 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P47047) MTR4_YEAST IPR025696 (rRNA-processing arch domain)
The essential RNA helicase Mtr4 is an exosome-activating cofactor
602 872 18.0/18.0 [mitab][xml]
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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