The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004600 Q9C0E8-2 LNPK
LNP_HUMAN
198 203 GPPKDSSAPGGPPERTVTPA TP --- Homo sapiens (Human) 423

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0033 deletion analysis Yuniati,2020 support certain FeatureDetection
experimental MI:0573 mutation disrupting interaction in vivo/in vitro Yuniati,2020 support certain
experimental MI:0007 anti tag coimmunoprecipitation in vivo Yuniati,2020 support certain InteractionDetection
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Yuniati,2020 support certain FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q53G59) KLH12_HUMAN IPR006652 (Kelch repeat type 1)
Kelch is a 50-residue motif, named after the Drosophila mutant in which it was first identified
281 567 [mitab][xml]
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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