The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004590 P34244 HSL1
HSL1_YEAST
827 835 EEQKPKRAALSDITNSFNKM TP --- Saccharomyces cerevisiae (Baker"s yeast) 1518

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0119 mutation decreasing interaction in vivo/in vitro Burton,2001 support certain InteractionDetection
experimental MI:0517 radiolabel in vitro Burton,2001 support certain
experimental MI:0007 anti tag coimmunoprecipitation in vivo Burton,2001 support certain InteractionDetection
experimental MI:0113 western blot in vitro Burton,2001 support certain ParticipantIdentification FeatureDetection
experimental MI:0997 ubiquitinase assay in vitro Choi,2008 support certain InteractionDetection
experimental MI:0007 anti tag coimmunoprecipitation in vivo Choi,2008 support certain InteractionDetection
experimental MI:0517 radiolabel in vitro Ostapenko,2008 support certain
experimental MI:0997 ubiquitinase assay in vitro Ostapenko,2008 support certain InteractionDetection
experimental MI:0997 ubiquitinase assay in vitro Frye,2013 support certain InteractionDetection
experimental MI:0997 ubiquitinase assay in vitro He,2013 support certain InteractionDetection
experimental MI:0405 competition binding in vitro He,2013 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P26309) CDC20_YEAST IPR015943 (WD40/YVTN repeat-like-containing domain superfamily)
This superfamily represents a WD40/YVTN repeat-like domain
198 556 [mitab][xml]
(P53197) CDH1_YEAST IPR015943 (WD40/YVTN repeat-like-containing domain superfamily)
This superfamily represents a WD40/YVTN repeat-like domain
241 548 [mitab][xml]

o  Pathways

KEGG: The sequence P34244 is implicated in the following 2 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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