| Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
|---|---|---|---|---|---|---|---|---|
| ELMI004557 | O14640 DVL1 DVL1_HUMAN |
657 | 662 | AYTVVGGPPGGPPVRELAAV | TP |
6TTK |
Homo sapiens (Human) | 695 |
Instance evidence
| Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
|---|---|---|---|---|---|---|---|
| experimental | MI:0119 | mutation decreasing interaction | in vivo/in vitro | Chen,2020 | support | certain | InteractionDetection |
| experimental | MI:0033 | deletion analysis | Chen,2020 | support | certain | FeatureDetection | |
| experimental | MI:0081 | peptide array | Chen,2020 | support | certain | InteractionDetection | |
| experimental | MI:0573 | mutation disrupting interaction | in vivo/in vitro | Chen,2020 | support | certain | |
| experimental | MI:0997 | ubiquitinase assay | in vitro | Chen,2020 | support | certain | InteractionDetection |
| experimental | MI:0007 | anti tag coimmunoprecipitation | in vivo | Chen,2020 | support | certain | InteractionDetection |
| experimental | MI:0053 | fluorescence polarization spectroscopy | in vitro | Chen,2020 | support | certain | InteractionDetection |
| experimental | MI:0005 | alanine scanning | in vivo/in vitro/in silico | Chen,2020 | support | certain | FeatureDetection |
| experimental | MI:0074 | mutation analysis | in vivo/in vitro | Chen,2020 | support | certain | FeatureDetection |
| experimental | MI:0114 | x-ray crystallography | in vitro | Chen,2020 | support | certain | InteractionDetection FeatureDetection |
Interactions
| Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
|---|---|---|---|---|---|
| (Q53G59) KLH12_HUMAN | IPR006652
(Kelch repeat type 1)
Kelch is a 50-residue motif, named after the Drosophila mutant in which it was first identified |
281 | 567 | 22.3/22.3 | [mitab][xml] |
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement