The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004550 Q13009 TIAM1
TIAM1_HUMAN
1572 1578 LESASEEVIWVRREDFAPSR TP --- Homo sapiens (Human) 1591

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0807 comigration in gel electrophoresis in vitro Stafford,2011 support likely InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Stafford,2011 support likely FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(O14936) CSKP_HUMAN IPR000719 (Protein kinase domain)
Protein phosphorylation, which plays a key role in most cellular activities, is a reversible process mediated by protein kinases and phosphoprotein phosphatases
12 276 [mitab][xml]

o  Pathways

KEGG: The sequence Q13009 is implicated in the following 7 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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