The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004527 Q96ST2 IWS1
IWS1_HUMAN
473 491 IADIFGESGDEEEEEFTGFN TP 6EMR  
Homo sapiens (Human) 819

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0077 nuclear magnetic resonance in vitro Sharma,2018 support certain InteractionDetection FeatureDetection
experimental MI:0077 nuclear magnetic resonance in vitro Tesina,2015 support certain InteractionDetection FeatureDetection
experimental MI:0065 isothermal titration calorimetry in vitro Tesina,2015 support certain InteractionDetection
experimental MI:0091 chromatography technology in vitro Tesina,2015 support certain InteractionDetection
experimental MI:0096 pull down in vivo/in vitro Tesina,2015 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(O75475) PSIP1_HUMAN IPR021567 (Lens epithelium-derived growth factor, integrase-binding domain)
Lens epithelium-derived growth factor (LEDGF), also known as transcriptional co-activator p75, is a chromatin-associated protein that protects cells from stress-induced apoptosis
349 449 4.7/8.7 [mitab][xml]
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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