| Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
|---|---|---|---|---|---|---|---|---|
| ELMI004519 | Q03164 MLL MLL1_HUMAN |
5 | 13 | MAHSCRWRFPARPGTTGGGG | TP |
3U85 4GQ6 |
Homo sapiens (Human) | 3969 |
Instance evidence
| Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
|---|---|---|---|---|---|---|---|
| experimental | MI:0074 | mutation analysis | in vivo/in vitro | Shi,2012 | support | certain | FeatureDetection |
| experimental | MI:0114 | x-ray crystallography | in vitro | Shi,2012 | support | certain | InteractionDetection FeatureDetection |
| experimental | MI:0053 | fluorescence polarization spectroscopy | in vitro | Grembecka,2010 | support | certain | InteractionDetection |
| experimental | MI:0005 | alanine scanning | in vivo/in vitro/in silico | Grembecka,2010 | support | certain | FeatureDetection |
| experimental | MI:0405 | competition binding | in vitro | Grembecka,2010 | support | certain | InteractionDetection |
| experimental | MI:0065 | isothermal titration calorimetry | in vitro | Grembecka,2010 | support | certain | InteractionDetection |
| experimental | MI:0077 | nuclear magnetic resonance | in vitro | Grembecka,2010 | support | certain | InteractionDetection FeatureDetection |
| experimental | MI:0074 | mutation analysis | in vivo/in vitro | Huang,2012 | support | certain | FeatureDetection |
| experimental | MI:0114 | x-ray crystallography | in vitro | Huang,2012 | support | certain | InteractionDetection FeatureDetection |
| experimental | MI:0065 | isothermal titration calorimetry | in vitro | Huang,2012 | support | certain | InteractionDetection |
| experimental | MI:0019 | coimmunoprecipitation | in vivo/in vitro | Huang,2012 | support | certain | InteractionDetection |
Interactions
| Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
|---|---|---|---|---|---|
| (O00255) MEN1_HUMAN | IPR007747
(Menin)
The tumour suppressor gene MEN1 is mutated in patients with a dominantly inherited tumour syndrome, multiple endocrine neoplasia type 1 (MEN1) |
1 | 614 | 0.053/0.053 | [mitab][xml] |
Pathways
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement