The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004162 Q5VZK9 CARMIL1
CARL1_HUMAN
982 999 KLEHFTKLRPKRNKKQQPTQ TP 3LK2  
3LK3  
Homo sapiens (Human) 1371

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0045 experimental interaction detection McConnell,2020 support certain InteractionDetection
experimental MI:0053 fluorescence polarization spectroscopy in vitro McConnell,2020 support certain InteractionDetection
experimental MI:0065 isothermal titration calorimetry in vitro McConnell,2020 support certain InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Edwards,2015 support certain InteractionDetection
experimental MI:0573 mutation disrupting interaction in vivo/in vitro Edwards,2015 support certain
experimental MI:0107 surface plasmon resonance in vitro Edwards,2015 support certain InteractionDetection FeatureDetection
experimental MI:0405 competition binding in vitro Hernandez-Valladares,2010 support certain InteractionDetection
experimental MI:0053 fluorescence polarization spectroscopy in vitro Hernandez-Valladares,2010 support certain InteractionDetection
experimental MI:0033 deletion analysis Hernandez-Valladares,2010 support certain FeatureDetection
experimental MI:0045 experimental interaction detection Hernandez-Valladares,2010 support certain InteractionDetection
experimental MI:0114 x-ray crystallography in vitro Hernandez-Valladares,2010 support certain InteractionDetection FeatureDetection
experimental MI:0096 pull down in vivo/in vitro Yang,2005 support certain InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Yang,2005 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P14315) CAPZB_CHICK PF01115 (F_actin_cap_B)
F-actin capping protein, beta subunit
6 240 0.01/0.186 [mitab][xml]
(P47756) CAPZB_HUMAN PF01115 (F_actin_cap_B)
F-actin capping protein, beta subunit
6 240 [mitab][xml]
(P47757) CAPZB_MOUSE PF01115 (F_actin_cap_B)
F-actin capping protein, beta subunit
6 240 [mitab][xml]
(P13127) CAZA1_CHICK PF01267 (F-actin_cap_A)
F-actin capping protein alpha subunit
17 282 [mitab][xml]
(P52907) CAZA1_HUMAN PF01267 (F-actin_cap_A)
F-actin capping protein alpha subunit
17 282 [mitab][xml]
(P47754) CAZA2_MOUSE PF01267 (F-actin_cap_A)
F-actin capping protein alpha subunit
17 282 [mitab][xml]
(Q5RKN9) Q5RKN9_MOUSE PF01267 (F-actin_cap_A)
F-actin capping protein alpha subunit
17 282 [mitab][xml]
(Q923G3) Q923G3_MOUSE PF01115 (F_actin_cap_B)
F-actin capping protein, beta subunit
6 240 0.009/0.012 [mitab][xml]
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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