Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
---|---|---|---|---|---|---|---|---|
ELMI004153 | P10600 TGFB3 TGFB3_HUMAN |
261 | 267 | NEDDHGRGDLGRLKKQKDHH | TP |
4UM9 |
Homo sapiens (Human) | 412 |
Instance evidence
Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
---|---|---|---|---|---|---|---|
experimental | MI:0411 | elisa | in vitro | Campbell,2020 | support | certain | InteractionDetection ParticipantIdentification |
experimental | MI:0074 | mutation analysis | in vivo/in vitro | Campbell,2020 | support | certain | FeatureDetection |
experimental | MI:0033 | deletion analysis | Dong,2014 | support | certain | FeatureDetection | |
experimental | MI:0053 | fluorescence polarization spectroscopy | in vitro | Dong,2014 | support | certain | InteractionDetection |
experimental | MI:0114 | x-ray crystallography | in vitro | Dong,2014 | support | certain | InteractionDetection FeatureDetection |
Interactions
Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
---|---|---|---|---|---|
(P06756) ITAV_HUMAN | PF01839
(FG-GAP)
FG-GAP repeat |
252 | 286 | 0.0058/0.0124 | [mitab][xml] |
(P05106) ITB3_HUMAN | PF00362
(Integrin_beta)
Integrin, beta chain |
133 | 381 | [mitab][xml] | |
(P18564) ITB6_HUMAN | PF00362
(Integrin_beta)
Integrin, beta chain |
128 | 375 | 0.0058/0.0124 | [mitab][xml] |
(P26012) ITB8_HUMAN | PF00362
(Integrin_beta)
Integrin, beta chain |
142 | 388 | [mitab][xml] |
Pathways
KEGG: The sequence P10600 is implicated in the following 28 Pathways: (color codes: This sequence=red, interacting sequence=orange)- AGE RAGE signaling pathway in diabetic complications
- Amoebiasis
- Cell cycle
- Cellular senescence
- Chagas disease
- Chronic myeloid leukemia
- Colorectal cancer
- Cytokine cytokine receptor interaction
- Diabetic cardiomyopathy
- Dilated cardiomyopathy
- FoxO signaling pathway
- Gastric cancer
- Hepatitis B
- Hepatocellular carcinoma
- Hippo signaling pathway
- Human T cell leukemia virus 1 infection
- Hypertrophic cardiomyopathy
- Inflammatory bowel disease
- Leishmaniasis
- MAPK signaling pathway
- Malaria
- Pancreatic cancer
- Pathways in cancer
- Renal cell carcinoma
- Rheumatoid arthritis
- TGF beta signaling pathway
- Toxoplasmosis
- Tuberculosis
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement