The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003883 P14317 HCLS1
HCLS1_HUMAN
376 382 PEPEPENDYEDVEEMDRHEQ TP --- Homo sapiens (Human) 486

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0074 mutation analysis in vivo/in vitro Lettau,2015 support certain FeatureDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Lettau,2015 support certain InteractionDetection
experimental MI:0113 western blot in vitro Lettau,2015 support certain ParticipantIdentification FeatureDetection
experimental MI:0096 pull down in vivo/in vitro Lettau,2015 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P16333) NCK1_HUMAN PF00017 (SH2)
SH2 domain
282 356 [mitab][xml]

o  Pathways

KEGG: The sequence P14317 is implicated in the following 5 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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