The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003882 Q14247 CTTN
SRC8_HUMAN
419 425 ERLPSSPVYEDAASFKAELS TP --- Homo sapiens (Human) 550

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Oser,2010 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Oser,2010 support certain FeatureDetection
experimental MI:0055 fluorescent resonance energy transfer Oser,2010 support certain InteractionDetection
experimental MI:0096 pull down in vivo/in vitro Oser,2010 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P16333) NCK1_HUMAN PF00017 (SH2)
SH2 domain
282 356 5.23/6.77 [mitab][xml]

o  Pathways

KEGG: The sequence Q14247 is implicated in the following 5 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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