Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
---|---|---|---|---|---|---|---|---|
ELMI003816 | Q12778 FOXO1 FOXO1_HUMAN |
322 | 328 | RTSSNASTISGRLSPIMTEQ | TP | --- | Homo sapiens (Human) | 655 |
Instance evidence
Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
---|---|---|---|---|---|---|---|
experimental | MI:0586 | inhibitor | Rena,2004 | support | certain | ||
experimental | MI:0113 | western blot | in vitro | Rena,2004 | support | certain | ParticipantIdentification FeatureDetection |
experimental | MI:0113 | western blot | in vitro | Rena,2002 | support | certain | ParticipantIdentification FeatureDetection |
experimental | MI:0424 | protein kinase assay | in vivo | Rena,2002 | support | certain | InteractionDetection |
Interactions
Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
---|---|---|---|---|---|
(P48729) KC1A_HUMAN | PF00069
(Pkinase)
Protein kinase domain |
17 | 259 | [mitab][xml] | |
(P48730) KC1D_HUMAN | PF00069
(Pkinase)
Protein kinase domain |
9 | 267 | [mitab][xml] |
Pathways
KEGG: The sequence Q12778 is implicated in the following 15 Pathways: (color codes: This sequence=red, interacting sequence=orange)- AGE RAGE signaling pathway in diabetic complications
- AMPK signaling pathway
- Cellular senescence
- FoxO signaling pathway
- Glucagon signaling pathway
- Human papillomavirus infection
- Insulin resistance
- Insulin signaling pathway
- Longevity regulating pathway
- Longevity regulating pathway multiple species
- Pathways in cancer
- Prostate cancer
- Shigellosis
- Thyroid hormone signaling pathway
- Transcriptional misregulation in cancer
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement