The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003816 Q12778 FOXO1
FOXO1_HUMAN
322 328 RTSSNASTISGRLSPIMTEQ TP --- Homo sapiens (Human) 655

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0586 inhibitor Rena,2004 support certain
experimental MI:0113 western blot in vitro Rena,2004 support certain ParticipantIdentification FeatureDetection
experimental MI:0113 western blot in vitro Rena,2002 support certain ParticipantIdentification FeatureDetection
experimental MI:0424 protein kinase assay in vivo Rena,2002 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P48729) KC1A_HUMAN PF00069 (Pkinase)
Protein kinase domain
17 259 [mitab][xml]
(P48730) KC1D_HUMAN PF00069 (Pkinase)
Protein kinase domain
9 267 [mitab][xml]

o  Pathways

KEGG: The sequence Q12778 is implicated in the following 15 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
feedback@elm.eu.org