The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003814 O15151 MDM4
MDM4_HUMAN
291 297 EDSKSLSDDTDVEVTSEDEW TP --- Homo sapiens (Human) 490

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0424 protein kinase assay in vitro Chen,2005 support certain InteractionDetection
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Chen,2005 support certain FeatureDetection
experimental MI:1297 phosphoamino acid analysis Chen,2005 support certain FeatureDetection
experimental MI:0586 inhibitor Chen,2005 support certain
experimental MI:0424 protein kinase assay in vivo Chen,2005 support certain InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Chen,2005 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P48729) KC1A_HUMAN PF00069 (Pkinase)
Protein kinase domain
17 259 [mitab][xml]

o  Pathways

KEGG: The sequence O15151 is implicated in the following 2 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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