| Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
|---|---|---|---|---|---|---|---|---|
| ELMI003743 | P46108 CRK CRK_HUMAN |
221 | 225 | GGPEPGPYAQPSVNTPLPNL | TP | --- | Homo sapiens (Human) | 304 |
Instance evidence
| Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
|---|---|---|---|---|---|---|---|
| experimental | MI:0065 | isothermal titration calorimetry | in vitro | Shigeno-Nakazawa,2016 | support | certain | InteractionDetection |
Interactions
| Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
|---|---|---|---|---|---|
| (P46108) CRK_HUMAN | PF00017
(SH2)
SH2 domain |
13 | 104 | 10.2/10.2 | [mitab][xml] |
Pathways
- Bacterial invasion of epithelial cells
- Chemokine signaling pathway
- Chronic myeloid leukemia
- ErbB signaling pathway
- Fc gamma R mediated phagocytosis
- Focal adhesion
- Growth hormone synthesis, secretion and action
- Human cytomegalovirus infection
- Human immunodeficiency virus 1 infection
- Insulin signaling pathway
- MAPK signaling pathway
- MicroRNAs in cancer
- Neurotrophin signaling pathway
- Pathways in cancer
- Rap1 signaling pathway
- Regulation of actin cytoskeleton
- Renal cell carcinoma
- Shigellosis
- Yersinia infection
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement