The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003685 P49915 GMPS
GUAA_HUMAN
321 325 DEDRTPRKRISKTLNMTTSP TP --- Homo sapiens (Human) 693

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Pfoh,2015 support likely InteractionDetection
experimental MI:0053 fluorescence polarization spectroscopy in vitro Pfoh,2015 support likely InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Pfoh,2015 support likely
experimental MI:0096 pull down in vivo/in vitro Pfoh,2015 support likely InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q93009) UBP7_HUMAN PF12436 (USP7_ICP0_bdg)
ICP0-binding domain of Ubiquitin-specific protease 7
620 865 28.0/36.0 [mitab][xml]

o  Pathways

KEGG: The sequence P49915 is implicated in the following 3 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
feedback@elm.eu.org