The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003619 Q62848 Arfgap1
ARFG1_RAT
407 415 ATKKAAPSTAADEGWDNQNW TP --- Rattus norvegicus (Norway rat) 415

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0405 competition binding in vitro Rawet,2010 support certain InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Rawet,2010 support certain InteractionDetection
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Rawet,2010 support certain FeatureDetection
experimental MI:0096 pull down in vivo/in vitro Rawet,2010 support certain InteractionDetection
experimental MI:0573 mutation disrupting interaction in vivo/in vitro Suckling,2015 support certain
experimental MI:0065 isothermal titration calorimetry in vitro Suckling,2015 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q66H80) COPD_RAT PF00928 (Adap_comp_sub)
Adaptor complexes medium subunit family
262 510 10.0/10.0 [mitab][xml]

o  Pathways

KEGG: The sequence Q62848 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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