The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003614 P54132 BLM
BLM_HUMAN
1322 1326 LDEEIPVSSHYFASKTRNER TP --- Homo sapiens (Human) 1417

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0065 isothermal titration calorimetry in vitro Dherin,2009 support certain InteractionDetection
experimental MI:0018 two hybrid in vivo Dherin,2009 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P40692) MLH1_HUMAN PF16413 (Mlh1_C)
DNA mismatch repair protein Mlh1 C-terminus
502 756 7.8/10.2 [mitab][xml]

o  Pathways

KEGG: The sequence P54132 is implicated in the following 2 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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