The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003613 Q9UQ84 EXO1
EXO1_HUMAN
503 507 AVVVPGTRSRFFCSSDSTDC TP --- Homo sapiens (Human) 846

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0065 isothermal titration calorimetry in vitro Dherin,2009 support certain InteractionDetection
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Dherin,2009 support certain FeatureDetection
experimental MI:0096 pull down in vivo/in vitro Dherin,2009 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P40692) MLH1_HUMAN PF16413 (Mlh1_C)
DNA mismatch repair protein Mlh1 C-terminus
502 756 16.5/18.3 [mitab][xml]

o  Pathways

KEGG: The sequence Q9UQ84 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
feedback@elm.eu.org