The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003580 Q96RL7 VPS13A
VP13A_HUMAN
839 849 SEDDSEEEFFDAPCSPLEEP TP --- Homo sapiens (Human) 3174

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
predicted MI:0101 sequence based prediction in silico Murphy,2016 support certain InteractionDetection
experimental MI:0573 mutation disrupting interaction in vivo/in vitro Yeshaw,2019 support certain
experimental MI:0096 pull down in vivo/in vitro Yeshaw,2019 support certain InteractionDetection
experimental MI:0007 anti tag coimmunoprecipitation in vivo Yeshaw,2019 support certain InteractionDetection
experimental MI:0367 green fluorescent protein tag in vivo Yeshaw,2019 support certain
experimental MI:0663 confocal microscopy in vivo/in vitro Yeshaw,2019 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q9P0L0) VAPA_HUMAN PF00635 (Motile_Sperm)
MSP (Major sperm protein) domain
14 120 [mitab][xml]
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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