The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003528 O00192 ARVCF
ARVC_HUMAN
960 962 AVRLVDAVGDAKPQPVDSWV TP --- Homo sapiens (Human) 962

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0084 phage display Ivarsson,2014 support certain InteractionDetection
experimental MI:0101 sequence based prediction in silico Guo,2012 support certain InteractionDetection
experimental MI:0018 two hybrid in vivo Guo,2012 support certain InteractionDetection
experimental MI:0089 protein array Wolting,2011 support likely InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Wolting,2011 support likely InteractionDetection
experimental MI:0416 fluorescence microscopy Laura,2002 support certain InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Laura,2002 support certain InteractionDetection
experimental MI:0096 pull down in vivo/in vitro Laura,2002 support certain InteractionDetection
experimental MI:0411 elisa in vitro Laura,2002 support certain InteractionDetection ParticipantIdentification
experimental MI:0084 phage display Laura,2002 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q96RT1) LAP2_HUMAN PF00595 (PDZ)
PDZ domain (Also known as DHR or GLGF)
1321 1407 14.0/14.0 [mitab][xml]
(Q8TBB1) LNX1_HUMAN PF00595 (PDZ)
PDZ domain (Also known as DHR or GLGF)
274 356 [mitab][xml]
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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