The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003255 Q13416 ORC2
ORC2_HUMAN
113 119 AKLASELAKTPQKSVSFSLK TP --- Homo sapiens (Human) 577

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0586 inhibitor Lee,2012 support certain
experimental MI:0424 protein kinase assay in vitro Lee,2012 support certain InteractionDetection
experimental MI:0424 protein kinase assay in vivo Lee,2012 support certain InteractionDetection
experimental MI:0256 rna interference in vivo Lee,2012 support certain InteractionDetection
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Lee,2012 support certain FeatureDetection
experimental MI:0421 identification by antibody Lee,2012 support certain ParticipantIdentification
experimental MI:0943 detection by mass spectrometry in vivo/in vitro Lee,2012 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P24941) CDK2_HUMAN PF00069 (Pkinase)
Protein kinase domain
4 286 [mitab][xml]

o  Pathways

KEGG: The sequence Q13416 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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