The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003254 Q12959 DLG1
DLG1_HUMAN
440 446 SSFLGQTPASPARYSPVSKA TP --- Homo sapiens (Human) 904

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0421 identification by antibody Narayan,2008 support certain ParticipantIdentification
experimental MI:0412 electrophoretic mobility supershift assay Narayan,2008 support certain InteractionDetection
experimental MI:0113 western blot in vitro Narayan,2008 support certain ParticipantIdentification FeatureDetection
experimental MI:0586 inhibitor Narayan,2008 support certain
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Narayan,2008 support certain InteractionDetection
experimental MI:0424 protein kinase assay in vivo Narayan,2008 support certain InteractionDetection
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Narayan,2008 support certain FeatureDetection
experimental MI:0424 protein kinase assay in vitro Narayan,2008 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P06493) CDK1_HUMAN PF00069 (Pkinase)
Protein kinase domain
4 287 [mitab][xml]
(P24941) CDK2_HUMAN PF00069 (Pkinase)
Protein kinase domain
4 286 [mitab][xml]

o  Pathways

KEGG: The sequence Q12959 is implicated in the following 6 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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